Conversion of acid chlorides to esters through addition of an alcohol
Description: Acid chlorides are converted to esters when treated with alcohols.
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Real-World Examples:
Org. Synth. 1932, 12, 1
DOI Link: 10.15227/orgsyn.012.0001
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Org. Synth. 1944, 24, 18
DOI Link: 10.15227/orgsyn.024.0018
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Org. Synth. 1944, 24, 41
DOI Link: 10.15227/orgsyn.024.0041
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Org. Synth. 1966, 46, 1
DOI Link: 10.15227/orgsyn.046.0001
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Org. Synth. 1971, 51, 96
DOI Link: 10.15227/orgsyn.051.0096
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Our textbook has this reaction shown only with acid chlorides, as well. Does the addition-elimination happen with other acid halides or just acid chloride?
do you have a mechanism explain the reaction between alcoholic alkoxide with acyl halide or anhydride to form ester ??
I’m interested in to make a reaction between alcohol and maleic anhydride , but i don’t know what is the mechanism of the reaction will occur ..
may you help me please ??
Thanks ,
Ameen
It’s the same as this, but there is no proton transfer step. Addition and then elimination.