Reduction of esters to aldehydes using DIBAL
Description: Esters can be reduced to aldehydes with diisobutylaluminum hydride (DIBAL), a bulky source of hydride ion.
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Hey, will lithium tri-tert-butoxyaluminum hydride work here, as well, or just for the acid halides? If not, why the selectivity?
Thanks in advance!
Yep – it will also reduce aldehydes. That’s why it’s important to use only 1 equivalent when reducing acid halides, otherwise you get full reduction to the alcohol.
what’s the meaning of Me on this diagram?
Me means “methyl”, or CH3
please tell me how 3 or 4 molecule of DIBAL are used to reduction of alkyl ester
give me detailed mechanism