Introduction to Acid-Base Reactions
Following up on the 4 major classes of reactions you encounter in Org 1, let’s look at the first of those four: acid base reactions.
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Nucleophilic Substitution Reactions – Introduction
Introduction to Nucleophilic Substitution Reactions Today starts a new series of posts on walking through one of the key classes of reaction in organic chemistry:
Read moreNucleophiles and Electrophiles
Nucleophiles and Electrophiles, Nucleophilicity and Electrophilicity All through the series on understanding where electrons are, and how they flow, we’ve been talking about how the
Read moreAcid Base Reactions In Organic Chemistry
An Introduction to Acid Base Reactions In Organic Chemistry Now that we’ve described how to figure out where the electrons are in a molecule, the
Read moreThe Stronger The Acid, The Weaker The Conjugate Base
Basicity In Organic Chemistry: Some Basicity Trends Today we’ll look at a simple periodic basicity trend across the periodic table and extrapolate from it some
Read moreWalkthrough of Acid-Base Reactions (3) – Acidity Trends
Acidity Trends In Organic Molecules Here, we’ll review the key trends that affect acidity, which all have the common effect of stabilizing negative charge (or more broadly,
Read moreFive Key Factors That Influence Acidity
Five Key Factors That Affect Acidity Today we’ll talk about what’s behind the trends in acidity for different molecules and discuss the most important factors
Read moreAcid-Base Reactions: Introducing Ka and pKa
The Acidity Constant Ka (And Its Negative Logarithm pKa ) Is An Extremely Useful Measure Of Acidity So last time we went through all the
Read moreHow to Use a pKa Table
Today we’ll talk about an incredibly important skill that might take some time to grasp but pays tremendous dividends. We’ll go through the exact details of how to use a pKa table. Understanding the proper use of a pKa table will give you the ability to recognize which acid-base reactions will happen and which will not. This will come up a lot as you progress through Org 1 and Org 2. It might be helpful to go back and review some of the factors that affect acidity that were talked about earlier.
Read moreNucleophilicity vs. Basicity
Understanding The Differences Between Nucleophilicity vs Basicity Following up on Nucleophiles and Electrophiles, here’s a common question students have about nucleophilicity: 1. What’s the difference
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