Stereochemistry of the Diels-Alder Reaction
Stereochemistry of the Diels-Alder Reaction The Diels-Alder reaction always has the same pattern of bonds that form and break. Three pi bonds are broken, and
Read moreRules For Aromaticity
Rules For Aromaticity: The 4 Key Factors In the last post we introduced the concept of aromaticity, a property of some unusually stable organic molecules such
Read moreHuckel’s Rule: What Does 4n+2 Mean?
Hückel’s Rule: What Does 4n+2 Mean? “4n+2 is not a formula that you apply to see if your molecule is aromatic. It is a formula
Read moreThe Strecker Synthesis of Amino Acids
The Strecker Amino Acid Synthesis The Strecker synthesis is a two-step procedure for the synthesis of amino acids. It begins with the addition of cyanide
Read moreIntroduction to Peptide Synthesis
Peptide bonds: Forming peptides from amino acids with the use of protecting groups Today we’ll go deeper on how to synthesize the most important amides
Read moreReactions of Diazonium Salts: Sandmeyer and Related Reactions
Diazonium Salts From Amines, And Reactions Of Diazonium Salts Today let’s talk about a set of reactions of aromatic amines, that variously are catalogued under
Read moreExo vs Endo Products In The Diels Alder: How To Tell Them Apart
Today we’ll cover how to tell endo– and exo- products apart in the Diels-Alder reaction. Shortcut below. For the long-winded walkthrough with lots of examples, read more below. Table
Read moreAromatic, Non-Aromatic, or Antiaromatic? Some Practice Problems
Aromatic vs Antiaromatic vs Non Aromatic Practice Exercises Our last post in this series on aromaticity went through the 4 conditions a molecule must fulfill
Read moreHOMO and LUMO In the Diels Alder Reaction
The HOMO and LUMO In The Diels Alder Reaction The Diels-Alder reaction is a concerted reaction between a diene (with 4 pi-electrons) and a dienophile
Read moreAntiaromatic Compounds and Antiaromaticity
Antiaromatic Compounds Are Unusually Unstable What are the key factors that determine whether a molecule is antiaromatic? It is similar to the requirements for aromaticity,
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