Alkyne Hydroboration With “R2BH”
Hydroboration-Oxidation of Alkynes As seen in the previous chapter, hydroboration of alkenes with borane (BH3) followed by oxidation (NaOH, H2O2) gives alcohols with anti-Markovnikov regioselectivity
Read moreHow John Pulled Up His Organic Chemistry Exam Grades
The other week, loyal reader “John” (not his real name) wrote in to tell me how he had pulled up his exam grade in organic
Read moreHydration and Oxymercuration of Alkynes
Hydration and Oxymercuration of Alkynes Via Keto-Enol Tautomerism Alkyne chemistry bears many resemblances to alkene chemistry, but in these first few posts on the subject,
Read moreHydrohalogenation of Alkynes
Alkyne Hydrohalogenation – Addition of HX To Alkynes – HCl, HBr, and HI In the previous three posts on alkynes we’ve introduced some new reactions
Read moreAlkyne Halogenation: Bromination, Chlorination, and Iodination of Alkynes
Halogenation of Alkynes With Cl2, Br2, and I2 Like alkenes, alkynes can undergo halogenation with Cl2, Br2, or I2. When 1 equivalent of the halogen
Read moreAlkyne Reactions – The “Concerted” Pathway
Alkyne Reaction Mechanisms That Pass Through A “Concerted” Pathway – Cyclopropanation, Hydrogenation, Hydroboration Various reactions that proceed through a concerted mechanism such as hydrogenation, hydroboration,
Read moreOrganic Reaction Flashcards Version 2.0 Is Here!
Do you ever study by making flashcards of reactions? You might recall that a few months ago Rich Apodaca (of Metamolecular) and myself released the
Read moreAlkenes To Alkynes Via Halogenation And Elimination Reactions
Formation of Alkynes Via Double Elimination Of Halides Alkynes can be produced from vicinal or geminal dihalides through double elimination reactions. The usual choice of
Read moreAlkynes Are A Blank Canvas
Alkynes: The Gateway To Organic Synthesis Now that we’ve gone through all the major reactions of alkynes, we can take a step back and look
Read moreAnother Exercise In Mind Reading
Here’s another great example of how one reagent used in a certain context performs one thing, and in a different context performs a completely different
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