Hydroboration Oxidation of Alkenes In this article we cover one of the most important methods for forming alcohols from alkenes, hydroboration-oxidation. Hydroboration is an addition reaction between an alkene
Read morem-Chloroperoxybenzoic Acid (m-CPBA) For The Epoxidation of Alkenes m-CPBA (meta-chloroperoxybenzoic acid) is a useful reagent for the formation of epoxides from alkenes (note – often
Read moreOsmium tetroxide, OsO4 Osmium tetroxide (OsO4) is a useful reagent for the dihydroxylation of alkenes The products of these reactions are 1,2-diols (“vicinal” diols), where the two
Read moreCatalytic Hydrogenation of Alkenes With Pd/C (And Friends) Alkenes (and alkynes) will undergo addition of hydrogen (H2) in the presence of a metal catalyst such
Read moreToday, in partnership with Rich Apodaca of Metamolecular, I’m happy to announce the release of a new app for the Apple iOs: Organic Reaction Flashcards
Read moreLoyal reader “Nathan” (not his real name) sent in this note recently on how he managed to do well in organic chemistry without it having
Read moreCyclopropanation of Alkenes Alkenes can undergo addition reactions from carbenes to give cyclopropanes. There are three main pathways for this reaction that are generally covered in introductory
Read moreThe “Three-Membered Ring” Pathway In Alkene Mechanisms: Halogenation, Oxymercuration, Halohydrin Formation, and Acidic Epoxide Opening In the last post we walked through a proposal for
Read moreFollowing up on the 4 major classes of reactions you encounter in Org 1, let’s look at the first of those four: acid base reactions.
Read moreSN1 vs E1, and SN2 vs. E2: The Role Of Heat This article assumes you understand the mechanisms of the SN1/SN2/E1 and E2 reactions. For
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