Grignard Reagents For Addition To Aldehydes and Ketones
Grignard Reagents: Their Formation, Reactions, And Reaction Mechanisms Today’s reagent is one that most students have experience in making at some point or another. Grignard
Read moreGrignard Reagents: Their Formation, Reactions, And Reaction Mechanisms Today’s reagent is one that most students have experience in making at some point or another. Grignard
Read moreUnderstanding The Differences Between Nucleophilicity vs Basicity Following up on Nucleophiles and Electrophiles, here’s a common question students have about nucleophilicity: 1. What’s the difference
Read moreMy one-sentence advice to those about to write an exam: Number your carbons. Now go write your exam. If you need reasons, here they are.
Read moreFactors That Determine Whether A Species Is A Good Nucleophile If you read the last post, you’ll recall that a nucleophile is a species that
Read moreGood Leaving Groups Are Weak Bases A leaving group (a.k.a. “nucleofuge”) is the new Lewis base that is generated in various substitution and elimination reactions when
Read moreCarbocations: Properties, Formation, and Stability Carbocations are electron-deficient species with an empty p-orbital Lacking a full octet and bearing a positive charge, they tend to
Read moreI can’t claim credit for this idea but unfortunately I can’t remember where I read it either. Here’s a helpful and quick way to make
Read moreOne kcal/mol is actually a lot This article discusses the relationship between the equilibrium constant K and the difference in energy ΔG, and explores some
Read moreCousins Of The Diels-Alder: The Cope Rearrangement and The Claisen Rearrangement The Cope Rearrangement and Claisen Rearrangement are pericyclic reactions in the same family as
Read moreLoyal reader Sandy writes in with a comment about memorization: I wish I had understood much earlier that there is a place for memorization in
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