Nucleophilic Substitution Reactions – Introduction
Introduction to Nucleophilic Substitution Reactions Today starts a new series of posts on walking through one of the key classes of reaction in organic chemistry:
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Two Types of Nucleophilic Substitution Reactions
Comparing Two Nucleophilic Substitution Reactions That Clearly Have Different Mechanisms Experiments tell us that nucleophilic substitution reactions generally fall into two main groups: In one group: The reaction
Read moreThe SN2 Mechanism
The SN2 Reaction Mechanism Having gone through the two different types of substitution reactions, and talked about nucleophiles and electrophiles, we’re finally in a position
Read moreWhy the SN2 Reaction Is Powerful
SN2 Reaction Examples To Give Alcohols, Ethers, Thiols, Sulfies, Alkynes, and More. Having gone through the mechanism of the SN2 reaction, let’s take a second
Read moreThe SN1 Mechanism
The SN1 Reaction Mechanism There are two important classes of nucleophilic substitution mechanisms – the SN1 and SN2 mechanisms (See article – Two Types of
Read moreThe Conjugate Acid Is A Better Leaving Group
Adding Acid Increases Leaving Group Ability Sure, it’s one thing to recognize halogens (Cl, Br, and I) as having high leaving group ability, as well
Read moreComparing the SN1 and SN2 Reactions
Comparing the SN1 and SN2 Reactions In nucleophilic substitution reactions, a bond between carbon and a leaving group (C–LG) is broken, and a new bond
Read morePolar Protic? Polar Aprotic? Nonpolar? All About Solvents
Polar Protic vs Polar Aprotic vs Nonpolar: About Solvents In Organic Chemistry A lot of students I talk to have questions about solvents. Solvents can
Read moreSteric Hindrance is Like a Fat Goalie
Steric Hindrance In Nucleophilic Substitution Reactions Sportswriter Todd Gallagher asked a question that every hockey fan has probably asked at one point. “Could a morbidly
Read moreCommon Blind Spot: Intramolecular Reactions
Intramolecular Reactions So I bought a belt today (pleather, 75 cents at the Goodwill). and decided to show it off. This is me putting it
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