…carbon at the beginning of the name. Hence the molecule above is (1R, 3R, 4S)-3-bromo-4-ethyl-1-methyl-1-propylcyclopentane. If you want to see exactly how the assignment for the (S) configuration was made,…
Read more…a publication. Nucleophilic Reactivities of Primary and Secondary Amines in Acetonitrile Tanja Kanzian, Tobias A. Nigst, Andreas Maier, Stefan Pichl, Herbert Mayr J. Org. Chem. 2009, 36, 6379-6385 DOI: 10.1002/ejoc.200900925…
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Read more…cents/ day! Real-Life Examples: Org. Synth. 1932, 12, 12 DOI Link: 10.15227/orgsyn.012.0012 Click to Flip Org. Synth. 1949, 29, 38 DOI Link: 10.15227/orgsyn.029.0038 Click to Flip Org. Synth. 1940, 20,…
Read moreWhy are halogens ortho-, para- directors? All activating groups are also ortho-, para- directors. Halogens (F, Cl, Br, I) are notable in that they are deactivating ortho-, para- directors. Why?…
Read moreOrtho-, Para– and Meta– Directors In Electrophilic Aromatic Substitution (EAS), some substituents on benzene will direct the electrophile E to the ortho– (1,2)and para– (1,4) positions. These are called, “ortho,…
Read more…enolates, amines, thiolates [RS(-)], enamines and dialkylcuprates (“Gilman reagents”) Grignard reagents do not perform conjugate addition; they add to carbonyl carbons instead (“1,2-addition”), as do organolithium reagents and LiAlH4. Table…
Read more…Org 1 / Org 2 summary sheets, and flashcards, sign up here for only 30 cents/ day! Real-Life Example Org. Synth. 1961, 41, 76 DOI Link: 10.15227/orgsyn.041.0076 Click to Flip…
Read more…took it? I made sure that I understood Chem 2!! Also, I made sure I could master resonance structures! What’s the “reason why” for you? Why spend all this time…
Read more…Ber. 1884, 17 (2), 2544-2547 DOI: 10.1002/cber.188401702178 Ueber eine einfache Methode der Darstellung von Benzoësäureäthern Baumann, E. Ber. 1886, 19 (2), 3218-3222 DOI: 10.1002/cber.188601902348 Enantioselective Total Synthesis of (−)-Kibdelone C…
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