…reactions with examples, mechanisms, and applications. Table of Contents The Cope Rearrangement: Example And Mechanism The Cope Rearrangement Is An Equilibrium Cope-ing With Ring Strain The Oxy-Cope Rearrangement The Claisen…
Read more…“For Free” By Lowering The Temperature Up until now we’ve been examining the relationship between free energy and equilibrium constant at room temperature (298 K) What happens to the equilibrium…
Read more…structure and properties of the vast majority [Note 2] of carbocations closely resemble those of neutral boron compounds. Both carbocations and neutral boron compounds generally have an sp2-hybridized central atom…
Read moreGood Leaving Groups Are Weak Bases A leaving group (a.k.a. “nucleofuge”) is the new Lewis base that is generated in various substitution and elimination reactions when a new bond is…
Read moreMy one-sentence advice to those about to write an exam: Number your carbons. Now go write your exam. If you need reasons, here they are. There’s two. First reason: if…
Read more…to form a new covalent bond. Nucleophilicity is measured by comparing reaction rates; the faster the reaction, the better (or, “stronger”) the nucleophile. Table of Contents Reminder: Nucleophilicity Is Measured…
Read more…essentially the conjugate bases of alkanes, they’re also extremely strong bases. This means that sometimes acid-base reactions can compete with their nucleophilic addition reactions. One common situation where this crops…
Read more…Don’t forget – you can download a free 1-page Summary Sheet of SN1 vs SN2 reactions containing all the material on this blog post here: Download SN1 vs SN2 Summary…
Read more…PDF VERSION NOW AVAILABLE (click here) For more complete lists, be sure to check out Evans and Reich. (check out the resources on Reich’s page by the way – fantastic!)…
Read more…experimentally). A strong acid has complete or nearly complete dissociation, so a large Ka. A weak acid has incomplete dissociation, and a small Ka. Not shown in the equation for…
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