…p.43 (1978). DOI: 10.1021/orgsyn.058.0043 A reliable procedure for the Upjohn dihydroxylation in Organic Syntheses. Note that the name comes from the Upjohn company in Kalamazoo, MI (later acquired by Pfizer),…
Read more…its charge remains the same. Here’s two more examples – an example with three arrows, and an exaggerated (but plausible) example with six (!!!) arrows. Notice that no matter how…
Read more…is distinct from the SN2 in three distinct ways. The reaction is fastest for tertiary alkyl halides and slowest for primary (and methyl) halides The rate law is unimolecular –…
Read more…charged anions, COT2− exists in isolation only… as a short-lived resonance state lying above neutral COT” “….Charge-compensating complexation of COT2−with two sodium cations results in a thermodynamically stable Na2COT compound”…
Read more…Bicyclic Compounds – A Five-Step Guide A Few More Examples Of Bridged Bicyclic Molecules Naming Spiro Compounds Summary: Naming Bicyclic Compounds Notes (and a complex example) (Advanced) References and Further…
Read more…of “America’s Top TA” in an online contest sponsored by the learning company CengageBrain. This article in NJ.com should give you an idea why: In his first week as a…
Read more…Matthias Bickelhaupt ChemPhysChem 2018, 19 (11), 1315-1330 DOI: 1002/cphc.201701363 A more recent paper computationally examining the effects of various variables on SN2 reaction energetics. Solvolytic Displacement Reactions At Saturated Carbon…
Read more…serve as a counterpoint. In the second example, it is the tertiary substrate that reacts fastest, followed by the primary substrate. Interesting! 2. How Two Nucleophilic Substitution Reactions Vary According…
Read more…recent offering of massively open online courses (MOOC’s) in the fall. If the type of thinking required for solving the types of problems encountered in organic chemistry can be taught…
Read more…question when understanding a new reaction: where are the electrons in our starting materials? 2. The Two Reactive Partners In A Substitution Reaction Are An Electron-Rich “Nucleophile” And An Electron-Poor…
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