…reactions so far (free-radical halogenation), our “reaction map” was very small. Table of Contents Key Transformations of Alkyl Halides Substitution Reactions of Alkyl Halides: Why The SN2 Is Powerful What…
Read more…Reactions In Comprehensive Introductory Organic Chemistry Textbooks Donna J. Nelson Proceedings of the Oklahoma Academy of Sciences 2022, 102, 105-114 DOI: Direct link (PDF) A comparison of how 17 commonly…
Read more…Brandon J. Karlow, and Jean E. Schneider The Journal of Organic Chemistry 2014 79 (3), 867-879 DOI: 10.1021/jo4026644 A more recent article about competition between SN2 and E2 reactions. https://www.sciencedirect.com/science/article/abs/pii/S0040402001972503…
Read moreToday, in partnership with Rich Apodaca of Metamolecular, I’m happy to announce the release of a new app for the Apple iOs: Organic Reaction Flashcards for iPhone. It should come…
Read moreToday I’ll share with you one thing about organic chemistry that made me feel really, really dumb when I took it. And looking back, I didn’t need to. So if…
Read more…you later realize you do need to test yourself on it, bringing it back is easy to do. 3. Self testing The testing aspect of Flashcards is one of…
Read more…for studying organic chemistry? Chris: I made note cards to learn reactions (with examples and mechanism) and exam problems from previous semesters that my professor taught. MOC: How much time…
Read more…products is clear. However it isn’t always as dramatic as it is in the first example. Here are some examples from an early paper (J. Chem. Soc. 1948, p. 2049)…
Read more…this reaction ends up being a wash: treatment with NaBH4 leads to cleavage of the C-Hg bond and formation of a free radical. The free radical can react from either…
Read more…a concerted mechanism. (Reactions that aren’t stereospecific, such as addition of H-X to alkenes, and free-radical addition of H-Br to alkenes, tend to proceed through carbocation or free-radical intermediates that…
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