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…no obligation (1) to maintain any comments in confidence; (2) to pay compensation for any comments; or (3) to respond to any comments. We may, but have no obligation to,…

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The Robinson Annulation

Description: The Robinson annulation is a method for forming six membered rings. It is a sequential combination of the Michael reaction and the Aldol condensation. The rest of this page…

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Free Radical Reactions

“free radical substitution”. In this post we introduce the concepts of homolytic bond breakage, single-barbed curved arrows, free radicals, and free-radical substitution through the example of chlorination of alkanes with…

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The Mannich Reaction

…iminium). The rest of this page is available to MOC Members only. To get access to this page, plus over 2500 quizzes, the Reaction Encyclopedia, Org 1 / Org 2…

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The Malonic Ester Synthesis

Description: The Malonic Ester Synthesis is a method for making substituted carboxylic acids. It is a combination of three reactions: 1) deprotonation, 2) alkylation, 3) acidic ester hydrolysis, and 4)…

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The Heck Reaction

…MOC Members only. To get access to this page, plus over 2500 quizzes, the Reaction Encyclopedia, Org 1 / Org 2 summary sheets, and flashcards, sign up here for only…

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Aromaticity Practice Quizzes

…a MOC member to see the clickable quiz with answers on the back. Quiz#: 1023 Become a MOC member to see the clickable quiz with answers on the back. Quiz#:…

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Epoxide Reaction Quizzes

…Click to Flip Quiz#: 1377 Click to Flip Quiz#: 1379 Click to Flip Quiz#: 1380 Become a MOC member to see the clickable quiz with answers on the back. Quiz#:…

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