…configuration (SN2) You might be asking, “how common is this SNi mechanism? Is it something which occurs in a large number of other reactions we commonly encounter in introductory organic…
Read moreWhen I ask my students what their goal for the course is, the most common answer is this: “To get an A”. I don’t know how to guarantee getting a…
Read more…people take in college. First semester I made a Pass, or a B/C. For some reason I just couldn’t make an A on any of this guys’ tests. The material…
Read more…that is commonly encountered in Org 1/ Org 2. In organic chemistry, sometimes you need to build molecules up. Other times, you need to break molecules down. Ozone, which we…
Read more…commonly encountered in Org 1/ Org 2. Sometime back in general chemistry you (hopefully) learned that hydroxide ion (HO-) is a strong base. It’s the conjugate base of water –…
Read more…Note 1. LiAlH(O-t-Bu)3 is commercially available as a solid or as a solution in THF or diglyme. It can also be prepared directly from LiAlH4 by adding three equivalents of…
Read more…Problems Intramolecular reactions [i.e. reactions where two functional groups in a molecule react with each other] cause a surprising amount of consternation on the part of students. These reactions come…
Read more…though he was the worst pitcher for the Braves that night. Them’s the rules. From http://hardballtalk.nbcsports.com/2014/04/15/that-was-some-win-for-luis-avilan-last-night/ Somewhere, Harvey Haddix is shaking his fist, asking “where is the justice?” A long…
Read more…state in the Cope Rearrangement W. von E. Doering, W. R Roth Tetrahedron, 1962, 18, 67-74 DOI: 10.1016/0040-4020(62)80025-8 In this classic study, von Doering and Roth proposed a six-membered ring…
Read more…References and Further Reading 1. But First: The Cats And The Comfy Chair But first – have you ever heard the story of the cats and the comfy chair? Cat…
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