…the Ortho-,Para- Director First; To Obtain the Meta- Product, Install the Meta- Director First Practice Questions Notes Quiz Yourself! 1. Synthesis of Aromatic Compounds: “Order Of Operations” Matters Up to…
Read more…Mechanism Behind This “Two Step” Pattern For Addition Reactions Of Aldehydes And Ketones Here’s the general mechanism. First comes addition of the nucleophile, and second comes protonation of the resulting…
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Read more…fairly easy. One common method is to convert the free amine into an amide with a reagent such as acetic anhydride (Ac2O). The resulting amide still an ortho- , para–…
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Read more…ureas and carbamates. The rest of this page is available to MOC Members only. To get access to this page, plus over 1500 quizzes, the Reaction Encyclopedia, Org 1 /…
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Read more…more acidic than it normally would be, because the resulting anion will be resonance stabilized. (Its pKa is 8.3 ) A common choice of base is a hydride base such…
Read more…We’ll have more to say about this when we address synthesis in aromatic compounds, but just take a gander at these two examples…. Two more examples of reversing the polarity…
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