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The Hofmann and Curtius Rearrangements

comparison to other similar reactions, and experimental procedures. UNDECYL ISOCYANATE F. H. Allen and Alan Bell Org. Synth. 1944, 24, 94 DOI: 10.15227/orgsyn.024.0094 An old but reproducible and tested procedure…

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The Hofmann Elimination

…to amines. 3. The “Hofmann Degradation” Back in 1851, not many techniques for analyzing complex molecules were available. One method for determining the structure of an unknown compound was to…

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s-cis and s-trans

…that there is free rotation about sigma bonds, so we say, “s-cis” and “s-trans” to distinguish it from “cis” and “trans” configurations which are locked. As we’ll soon see, in…

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Diels Alder Practice Problems

These practice questions will test you on recognizing conjugated dienes, comparing the reactivity of dienes in the Diels-Alder reaction, providing the major products of Diels-Alder reactions, understanding how to apply…

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