…8. Ketone Enolates This article would not be complete without briefly mentioning some of the complications that come with ketone enolates. In many cases treating a ketone with base could…
Read moreKinetic versus Thermodynamic Enolates of Ketones Enolates have a lot in common with alkenes. They are flat and have a C-C pi bond. Zaitsev’s rule reminds us that alkene stability…
Read more…how the Grignard reagent is made. Examples: Notes: The first product of the reaction is an imine, which is then hydrolyzed to the ketone with water (or mild aqueous acid)….
Read more…rest of this page is available to MOC Members only. To get access to this page, plus over 2500 quizzes, the Reaction Encyclopedia, Org 1 / Org 2 summary sheets,…
Read moreMOC Member Resources: Go to the Reaction Guide Go to the Practice Quizzes Download the Reaction Flashcards (PDF) Download the Org 1 Summary Sheets (PDF) Download the Org 2 Summary…
Read more…undergoes elimination (Step 5, form C-O (pi) break C-O) to give the protonated (new) ester, which then undergoes a final deprotonation (Step 6, break O-H) to give the new ester….
Read moreDescription: Addition of a Grignard reagent to an aldehyde results in a new C–C bond an a secondary alcohol after addition of acid. The rest of this page is available…
Read more200+ Printable Organic Reaction Flashcards Here’s the PDF of version 1 of Flashcards. Just a heads up – it’s pretty big (11 MB) – but has 210 reactions, front and…
Read more…any optical rotation. The same is true for (–)-erythrose, which returns a completely identical compound. From this it can be deduced that the structure of the new compound must be…
Read more…will be inversion of configuration. Another example: Opening of tetrahydrofuran (THF) with aqueous acid: Test Yourself! Click to Flip Click to Flip Click to Flip (Advanced) References and Further Reading…
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