…that much. If you take a solution of an enantiomerically pure, optically active ketone like this one [(S)-2-methylcyclohexanone] add a few drops of strong acid and stir overnight, you’ll come…
Read moreDescription: Enolates of carbonyl compounds will add to an α,β-unsaturated carbonyl compounds to give 1,5-dicarbonyl compounds. This is called the Michael reaction. The rest of this page is available to…
Read more…8. Ketone Enolates This article would not be complete without briefly mentioning some of the complications that come with ketone enolates. In many cases treating a ketone with base could…
Read more…Also, unlike alkoxide bases RO(-), deprotonation goes to completion. So long as an excess of base is used, there is no equilibrium between the different enolates. [Note 5] LDA is…
Read more…back. Note: if you are a member and don’t see a download link, you need to log in first. [Download link hidden – Join here] Each reaction answer has a…
Read more…issues that repeatedly come up to baffle students: Greek letters, and “1,2-” or “1,4-” addition reactions. In this post I’ll try to address them both. Table Of Contents The “Alpha…
Read more…through the two-step addition-elimination mechanism. Generally speaking the formation of five- and six-membered rings is favored relative to opening of the ring, for reasons related to entropy. [Note 2] 4….
Read moreHere is a quiz Become a member to see the clickable quiz with answers on the back. https://www.masterorganicchemistry.com/wp-content/uploads/2022/08/226-front-predict-product-e2-kotbu.gif https://www.masterorganicchemistry.com/wp-content/uploads/2022/08/226-front-predict-product-e2-kotbu.gif …
Read more…that they would like more examples of various reactions, as well as more examples of synthesis and spectroscopy problems. I’m looking for a few exceptional individuals who *love* putting together…
Read more…the molecule on the left is E-(2R, 5R)-5-chloro-hex-3-en-2-ol the molecule on the right is E-(2R, 5R)-5-chloro-hex-3-en-2-ol So how are they related? They’re not constitutional isomers (same connectivity!) But they’re not…
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