…122 (24), 5861-5865 DOI: 10.1021/ja000295g This paper examines computationally whether ‘Anti-Bredt’ olefins can be formed by formation of the bridgehead carbene followed by rearrangement. In the conclusion, the paper states,…
Read more…into acid chlorides (“acyl chlorides”). Here is a general example, along with some specific examples. The reaction also works with the related reagents PCl3, PCl5, and oxalyl chloride, which are…
Read more…Impossible The bad news – for memorizers, anyway – is that if your instructor tests you on your ability to apply concepts to various reactions, there is a near-infinite number…
Read moreNo doubt you’ve got some important exams coming up. With that in mind, here’s three simple tactics you can use during exams. 1. Draw partial charges If you get complete…
Read more…for. Finally, we come to this last example. We have a ketone and an ester. We can’t form a ring. You might think it would just add to the ketone…
Read more…the product for the hydrolysis of a cyclic amide (lactam) since reactions of cyclic molecules (and their reverse, intramolecular reactions) are common fodder for exams. This reaction comes up later…
Read more…over 80 reagents, including their structures, common names, reactions, and mechanisms -a quick-reference index, with 2 pages of condensed information on every reagent covered in the book. (Click here to…
Read more…sheet, here’s a page (PDF) with a “reaction map” of the most common reactions of organometallics that we discussed in the previous posts. Hope you find it useful! Here it…
Read more…Friday for the forseeable future here I will profile a different reagent that is commonly encountered in Org 1/ Org 2. Chromic Acid (H2CrO4) Is Equivalent To K2Cr2O7 + H2SO4…
Read more…gives this example. As Stewie said, Grossman’s rule is also useful for reactions. Here’s some common examples. Don’t you think including the hidden hydrogens makes it a bit clearer what’s…
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