Oxidative Cleavage of Alkynes with KMnO4
Description: Potassium permanganate (KMnO4) will cleave alkynes to give carboxylic acids.
The rest of this page is available to MOC Members only.
To get access to this page, plus over 2500 quizzes, the Reaction Encyclopedia, Org 1 / Org 2 summary sheets, and flashcards, sign up here for only 30 cents/ day!
what is the solvent for this
“With ordinary solutions of permanganate or dichromate yields are generally low, and the reaction is seldom a useful synthetic method; but high yields can be obtained by oxidizing with KMnO4 dissolved in benzene containing the crown ether 18-crown-6. The crown ether coordinates with K+ permitting the KMnO4 to dissolve in benzene. ” March’s Advanced Organic Chemistry 5th ed. p. 1526.
It is very nice explanation of Chemistry from Basic to Higher level. I am really happy
Thank ou Professor
i request for a mechanism for the cleavage of the tripple bonds by the pottasium permanganate
“Notes: Note where a terminal alkyne is being cleaved (examples 1 and 3) one of the products is carbon dioxide.”
You mean examples 2 and 4?
Yes. thanks, I’ll fix that!